Tom O'Brien


Prior to founding Eclipse in 1993, Tom held several leadership positions throughout his career in the medical device industry. Having mastered both disposable and capital equipment sales for companies like C.R. Bard, Tom’s track record of success quickly established Eclipse as the go-to company to launch new technology in the surgical laser industry.

Over time Tom transitioned Eclipse from a leader in the OR surgical laser market to a key player in the aesthetic laser industry. Starting in 2011 Eclipse began a new mission of increasing adoption of Platelet-rich Plasma on a national level.

His vision and leadership has helped Eclipse become one of the most successful medical device companies in its space. Tom’s new mission is to bring game-changing Eclipse technologies in Platelet-Rich Plasma, Microneedling and Shockwave Therapy to the entire globe.


Eclipse PRP®

The Eclipse PRP system utilizes a patented separator gel technology to isolate the platelets while eliminating the undesirable components such as red blood cells and inflammatory white blood cells.

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Easy Spin 3 Step Process

Step 1: Collect Patients Blood (11ml or 22ml tube) and Centrifuge (10 min.)

Step 2: Extract Platelet Poor Plasma (PPP)

Step 3: Collect Platelet Rich Plasma (PRP) and apply

What is Platelet-Rich Plasma?

Platelet-Rich Plasma (PRP) is an autologous concentrated preparation of platelets and the associated growth factors in a small volume of plasma. Platelets are a natural source of a number of growth factors in their natural and biologically-determined ratios.

What do Platelets do?

Platelets release growth factors which regulate the healing cascade by signaling to surrounding cells to repair damaged tissue and regenerate new tissue. Key growth factors involved in this process include but are not limited to:

  • Platelet-Derived Growth Factor (PDGF)
  • Transforming Growth Factor group (TGF)
  • Epidermal Growth Factor (EGF)
  • Vascular Endothelial Growth Factor (VEGF)
  • Fibroblast Growth Factor (FGF)
  • Keratinocyte Growth Factor (KGF)

What’s in the syringe matters!

• Platelet concentration in supraphysologic range

• Removes the most contaminating red blood cells

• Removes the most inflammatory white blood cells

Platelets – Supraphysiologic Range is Optimal

Animal in vitro Clinical Studies Support 1.5 – 3 X Baseline

Those methods with lower concentrations of platelets – 1 to 3 times baseline – showed more robust healing rates than those with higher concentrations 3 to 8 times baseline.1

The use of highly concentrated platelet preparations appeared to have an inhibitory influence…reasons could be unwanted inhibitory and cytotoxic effects of growth factors at such high concentrations.2

PRP might exert positive effects…in a dose-dependent manner up to a certain level, but adverse effects occur when it is highly concentrated.3

Optimal results were observed at a platelet concentration of 2.5 X...increased concentrations resulted in a reduction in proliferation and a suboptimal effect on osteoblast function.4

These data reject the hypothesis that increases the concentration of platelets in PRP is beneficial for articular cartilage and the meniscus; furthermore, these findings suggest that high platelet concentrations for intra-articular injection should be considered with caution.5


Vacuum Filled, Internally Coated Glass Tube designed to: • Prevent platelets from “sticking” to tube walls.
• Precisely draw blood at a pressure that prevents lysing of the cells

Proprietary Anti-Coagulant (MNC7) modified to • Reduce acidity while preventing coagulation of platelets.
• Deliver non-activated platelets physically positioned on top of gel

Patented Separator Gel designed to • Spare the 90% of platelets above
• Remove 99.9% of RBC below
• Remove 92% of granulocytes

Example Shown: 22mL Tube

5 Reasons to Avoid Red & White Blood Cells in PRP

  1. Lead to free radical formation6,7
  2. Inflammation6,7
  3. Vascular injury6,7
  4. Cell death (apoptosis)6,7
  5. May lead to Hemosiderin staining from iron oxide (rust). This is a permanent bruise.

  1. Release matrix metalloproteinases and produce oxygen radicals8
  2. Tissue damage8
  3. Inflammation9
  4. Impaired healing9
  5. Local pain10
There is no biologic rationale to include RBC or WBC in PRP preparations and their presence is based on the inability of other processing technologies to completely eliminate these cells from the PRP.

Cell Count & Growth Factor Statistics

Eclipse PRP
Platelet concentration fold*
RBC (106/ul)
WBC (103/ul)
Granulocytes %
Mononuclear cells %
PDGF (pg/ml)
VEGF (pg/ml)
EGF (pg/ml)

*An average of several independent, validated tests using the collection method outlined in this guide for the 11mL Eclipse PRP tube without the removal of PPP.
Eclipse PRP HC
Platelet concentration fold*
RBC (106/ul)
WBC (103/ul)
Granulocytes %
Mononuclear cells %
PDGF (pg/ml)
VEGF (pg/ml)
EGF (pg/ml)

*STD DEV. Mean concentration using 22ml tube, removing 6-7ml of platelet poor plasma (PPP) in patients with whole blood platelet counts ranging from 169,000 to 356,000 per microliter.

1. Rappl LM et al., Int Wound J 2011; 8:187-195.
2. Weibrich G et al., Bone 2004; 34:665-671.
3. Yamaguchi R et al., J Surg Res 2012; 173(2): 258-266.
4. Graziani F et al., Clin Oral Impl Res 2006; 17: 212-219.
5. Kisiday et al, Cartilage 2012; 3(3): 245-254.
6. Belcher et al., Antioxidants & Redox Signaling 2010; 12(2): 233-48.
7. Kumar et al., Toxicol lett 2005; 157 (3): 175-188.
8. Tidball, Am J Physiol Regul Integr Comp Physiol 2005; 288: R345-353.
9. Muylle, Transfusion 1993; 33(3): 195-199.
10. Mei-Dan, Br J Sports Med 2010; 44: 618-619.

Eclipse Difference

Simple: Fewer steps than other PRP (platelet-rich plasma) kits
Excellence: Optimal platelet recovery 87% ± 10%
Fast: Centrifuge with a single spin in a matter of minutes
Patient Friendly: Small volume of blood required
Excellent Value: High volume PRP yield, low cost per mL
~6 mL PRP per 11 mL tube
~12 mL PRP per 22 mL tube
Consistent Platelet Concentration: Allowing for predictable performance


1. PRP should be applied to the same patient from whom the blood was drawn.
2. Storage of tubes containing blood at or below 0°C may result in tube breakage.
3. Storage of tubes above 40°C may damage the gel stability.
4. Do not remove conventional rubber stoppers by rolling with a thumb. Remove stoppers with a twist and pull motion.
5. Do not use tubes if foreign matter is present.
6. All liquid preservatives and anticoagulants are clear. Do not use tubes after their expiration date.
7. Do not re-sterilize and do not attempt to clean this product.
8. Do not use products if pouch is damaged.
9. Use prepared platelet concentrate material within 4 hours after drawing blood from patient.

Possible Side Effects
Damage to blood vessels, hematoma, infection and/or irritation.
Temporary or permanent nerve damage that may result in pain or numbness.
As with any injection-based treatment, infection is a slight possibility.

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Regulatory Status

FDA cleared 510(k) Class II medical device. Eclipse PRP is intended for the safe and rapid preparation of autologous platelet-rich plasma (PRP) from a small sample of blood at the patient point of care. The PRP is mixed with autograft or allograft bone prior to application to a bony defect for improving handling characteristics. 510(k) number: BK110035